Analysis of 2 911 Isolated Strains and Bacterial Resistance to Antibiotics in Our Hospital in 2009

Objective: To analyze the change of clinical isolated strains and bacterial resistance to antibiotics in the hospital affiliated to Jiangsu University in 2009.Methods: The distribution and the antimicrobial susceptibility of pathogens,which were collected and isolated from all of the clinical specimens in 2009 in our hospital,were analyzed retrospectively by microsoft Excel 2003 program.Results: Totally 2 911 strains of pathogens were isolated,among which 2185 strains were Gram-negative bacteria (75.06%),536 strains were Gram-positive cocci (18.41%) and 190 strains were fungi (6.53%).The five common bacteria were Pseudomonas aeruginosa(16.32%),Acinetobacter baumanii (15.94%),Escherichia coli (12.09%),Klebsiella pneumoniae(11.78%),and Staphylococcus aureus(10.86%).Gram-positive cocci were more sensitive to vancomycin,teicoplanin,and nitrofurantoin than to other antibacteria.Meticillin-resistant S aureus(MRSA) accounted for 67.75%;vancomycin-resistant S aureus was not detected.Gram-negative bacilli had the lowest resistance to carbapenems,showing multi-resistance.Conclusion: Bacterial resistance is on the rise,and multi-resistance is getting more serious.Clinicians should control the change of drug-resistant spectrum of bacteria and conduct the rational use of clinical antibiotics according to drug susceptibility test.