2004•Bioorganic & Medicinal Chemistry LettersOpen access

Synthesis, topoisomerase I inhibition and structure–activity relationship study of 2,4,6-trisubstituted pyridine derivatives

Longxuan Zhao, Yoon‐Soo Moon, Arjun Basnet, Eun‐Kyung Kim, Yurngdong Jahng, Jae Gyu Park, Tae Cheon Jeong, Won‐Jea Cho, Sang‐Un Choi, Chong Ock Lee, Sun‐Young Lee, Chong-Soon Lee, Eung-Seok Lee

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Key concepts: Chemistry, Topoisomerase, Stereochemistry, Moiety, Pyridine, Structure–activity relationship, Biological activity, Chemical synthesis