Membrane‐associated and cytoplasmic fatty acid‐binding proteins
Frans A. van Nieuwenhoven, Ger J. Vusse, Jan F. C. Glatz
Abstract
Frans A. van Nieuwenhoven, Ger J. Vusse, Jan F. C. Glatz
Abstract
A number of cellular fatty acid-binding proteins are being implicated in the uptake and intracellular transport of long-chain fatty acids by parenchymal cells. Having been a topic of research for more than 20 years, cytoplasmic fatty acid-binding proteins now are assigned various pivotal functions in intracellular fatty acid transport and metabolism. More recently several membrane-associated fatty acid-binding proteins have been identified and these proteins are thought to function in the transmembrane transport of fatty acids. In this review, a short summary is provided of the latest developments in this research area.
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A number of cellular fatty acid-binding proteins are being implicated in the uptake and intracellular transport of long-chain fatty acids by parenchymal cells. Having been a topic of research for more than 20 years, cytoplasmic fatty acid-binding proteins now are assigned various pivotal functions in intracellular fatty acid transport and metabolism. More recently several membrane-associated fatty acid-binding proteins have been identified and these proteins are thought to function in the transmembrane transport of fatty acids. In this review, a short summary is provided of the latest developments in this research area.
Key concepts: Fatty acid-binding protein, Fatty acid, Biochemistry, adipocyte protein 2, Cytoplasm, Transmembrane protein, Intracellular, Free fatty acid receptor