1994•Bioorganic & Medicinal Chemistry LettersRequires access

New nonpeptide angiostensin II receptor antagonists. Synthesis, biological properties and structure-activity relationships of 3-substituted 2,6-dialkyl-4-(biphenyll)methylaminopyridine derivatives.

Robert H. Bradbury, Martin P. Edwards, Eric F. Fisher, J. Alan Girdwood, John S. Major, Alec A. Oldham, M.L. Patel, R. J. PEARCE, John Revill, Arnold H. Ratcliffe

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Key concepts: Chemistry, In vivo, Chemical synthesis, Biological activity, In vitro, Structure–activity relationship, Stereochemistry, Pharmacology