2007•Bioorganic & Medicinal ChemistryOpen access

Synthesis and SAR studies of a novel class of S1P1 receptor antagonists

Tsuyoshi Nakamura, Kiyoaki Yonesu, Yumiko Mizuno, Chie Suzuki, Yuki Sakata, Yoh Takuwa, Futoshi Nara, Susumu Satoh

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Key concepts: Chemistry, Lead compound, Stereochemistry, Chemical synthesis, Structure–activity relationship, Biphenyl, Sphingosine-1-phosphate, Side chain

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