2011•Biochemical PharmacologyOpen access

Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene

Lucie Krausová, Lucie Stejskalová, Hongwei Wang, Radim Vrzal, Zdeněk Dvořák, Sridhar Mani, Petr Pávek

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Key concepts: Pregnane X receptor, Constitutive androstane receptor, Transactivation, Nuclear receptor, Nuclear receptor coactivator 1, Metformin, Calcitriol receptor, CYP3A4

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Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene — Research Paper | ScholarLens