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2009•Drug Metabolism and DispositionOpen access

Methadone Induces the Expression of Hepatic Drug-Metabolizing Enzymes through the Activation of Pregnane X Receptor and Constitutive Androstane Receptor

Antonia H. Tolson, Haishan Li, Natalie D. Eddington, Hongbing Wang

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Key concepts: Pregnane X receptor, Constitutive androstane receptor, CYP2B6, CYP3A4, Pharmacology, Chemistry, Drug metabolism, Receptor

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Methadone Induces the Expression of Hepatic Drug-Metabolizing Enzymes through the Activation of Pregnane X Receptor and Constitutive Androstane Receptor — Research Paper | ScholarLens