2001•Biological and Pharmaceutical BulletinOpen access

Antiviral Amentoflavone from Selaginella sinensis

Shuang‐Cheng Ma, Paul Pui‐Hay But, Vincent Eng-Choon Ooi, Yuehua He, Spencer Hon‐Sun Lee, Song-Fong LEE, Rui‐Chao Lin

Abstract

Amentoflavone and three other flavonoids were isolated from the ethanol extract of Selaginella sinensis. Amentoflavone showed potent antiviral activity against respiratory syncytial virus (RSV), with an IC50 of 5.5 microg/ml. The contents of amentoflavone in nine species of Selaginella were determined by reversed-phase HPLC. S. sinensis showed a higher content of 1.13%.

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 146 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Amentoflavone, Selaginella, Biflavonoids, Traditional medicine, Chemistry, Biology, Pharmacology, Medicine