ScholarLens Back to search
1986•The Journal of DermatologyRequires access

The Inhibitory Effect of Selenium on Mice Inoculated with B16 Melanoma Cells

Katsumi Hanada, S. Satoh, Daisuke Sawamura, Isao Hashimoto, Yasuo Katabira

Open publisher page 7 citations

Abstract

Abstract The influence of selenium dioxide on the in vitro and in vivo growth of transplantable B16 melanoma was studied. In the in vivo study, melanoma tissues showed a decrease in development of tumor growth and a tendency toward higher levels of free radical signal (ESR). Cultured B16 melanoma cells revealed a marked disturbance of cell growth especially in the solution with a high dose of selenium. These results may indicate that selenium has an antitumorigenic effect on B16 melanoma cells.

About this research paper

What this paper is about

Abstract The influence of selenium dioxide on the in vitro and in vivo growth of transplantable B16 melanoma was studied. In the in vivo study, melanoma tissues showed a decrease in development of tumor growth and a tendency toward higher levels of free radical signal (ESR). Cultured B16 melanoma cells revealed a marked disturbance of cell growth especially in the solution with a high dose of selenium. These results may indicate that selenium has an antitumorigenic effect on B16 melanoma cells.

Why it matters

OpenAlex reports 7 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abstract The influence of selenium dioxide on the in vitro and in vivo growth of transplantable B16 melanoma was studied. In the in vivo study, melanoma tissues showed a decrease in development of tumor growth and a tendency toward higher levels of free radical signal (ESR). Cultured B16 melanoma cells revealed a marked disturbance of cell growth especially in the solution with a high dose of selenium. These results may indicate that selenium has an antitumorigenic effect on B16 melanoma cells.

Key concepts: Selenium, Melanoma, In vivo, In vitro, Cell growth, Chemistry, Cancer research, Inoculation

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The Inhibitory Effect of Selenium on Mice Inoculated with B16 Melanoma Cells — Research Paper | ScholarLens