1982•Journal of Toxicology Clinical ToxicologyRequires access

Successful Treatment of Paraquat Poisoning: Activated Charcoal per os and “Continuous Hemoperfusion”

Stefan Okonek, Ludwig Sacha Weilemann, Jozo Majdandzic, H. Setyadharma, Hans-Jürgen Reinecke, C. A. Baldamus, Julius Lohmann, K. E. Bonzel, Tomas Thon

Open publisher page 56 citations

Abstract

Ingestion of paraquat results in an extremely dangerous poisoning. The first aim is to clear the gastrointestinal tract by inducing emesis and performing gastric/gut lavage; as much activated charcoal as possible should be administered per os and as quickly as possible. The best measure to eliminate paraquat from blood and tissue is hemoperfusion with coated activated charcoal; it has to be performed in the sense of "continuous hemoperfusion" about 8 h/d over a period of 2-3 weeks. These measures give a chance to lower the lethality of paraquat poisoning.

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What this paper is about

Ingestion of paraquat results in an extremely dangerous poisoning. The first aim is to clear the gastrointestinal tract by inducing emesis and performing gastric/gut lavage; as much activated charcoal as possible should be administered per os and as quickly as possible. The best measure to eliminate paraquat from blood and tissue is hemoperfusion with coated activated charcoal; it has to be performed in the sense of "continuous hemoperfusion" about 8 h/d over a period of 2-3 weeks. These measures give a chance to lower the lethality of paraquat poisoning.

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OpenAlex reports 56 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Ingestion of paraquat results in an extremely dangerous poisoning. The first aim is to clear the gastrointestinal tract by inducing emesis and performing gastric/gut lavage; as much activated charcoal as possible should be administered per os and as quickly as possible. The best measure to eliminate paraquat from blood and tissue is hemoperfusion with coated activated charcoal; it has to be performed in the sense of "continuous hemoperfusion" about 8 h/d over a period of 2-3 weeks. These measures give a chance to lower the lethality of paraquat poisoning.

Key concepts: Hemoperfusion, Paraquat, Activated charcoal, Charcoal, Medicine, Anesthesia, Chemistry, Internal medicine

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Successful Treatment of Paraquat Poisoning: Activated Charcoal per os and “Continuous Hemoperfusion” — Research Paper | ScholarLens