Effect of environmental factors change on hemorheology of rabbits with myocardial ischemia.

Objective To observe the effect of environmental factors change on the hemorheology of the rabbit with myocardial ischemia.Methods The rabbits were divided into six groups,the group of myocardial ischemia(myocardial ischemia operation),the group of myocardial ischemia with hypoxia(volume fraction of oxygen of 91.5% nitrogen and 8.5% oxygen) and high temperature [(42±2)℃],the group of myocardial ischemia with hypoxia(volume of fraction of oxygen of 91.5% nitrogen and 8.5% oxygen),the group of myocardial ischemia with hypoxia(volume of fraction of oxygen of 91.5% nitrogen and 8.5% oxygen) and high temperature[(42±2)℃] and hunger(forbid water and fast in 24 h),the group of myocardial ischemia with hunger,control group,10 in each.After 30 minutes of treatment,the indexes of the hemorheology were determined.Results The changed environmental factors,hypoxia,high temperature,hunger,presented an increasing effect on the blood viscosity,plasma viscosity,blood high shear reduced viscosity,blood low shear reduced viscosity and equation K value of ESR(P0.05).In the groups of myocardial ischemia with hunger and myocardial ischemia,the erythrocyte rigidity index significantly increased(P0.05),in the group of myocardial ischemia with hunger have decrease(P0.05),in the group of myocardial ischemia with hunger,the erythrocyte aggregation index and erythrocyte deformation index increased significantly(P0.05).Conclusion The environmental factors change has an obvious effect on hemorheology of the rabbit with myocardial ischemia and hunger.