2009•Chinese Journal of New Clinical MedicineRequires access
The effect of hypoxia and high temperature on the microcirculation in the state of myocardial ischemia in rabbits
Huang Li-juan
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Abstract
Objective To observe the effect of hypoxia and high temperature on the microcirculation in the state of myocardial ischemia in rabbits.Methods Twenty rabbits were randomly divided into the myocardial ischemia groups and the hypoxia and high temperature of myocardial ischemia groups,after myocardial ischemia,the hypoxia and high temperature of myocardial ischemia group were put into a hypoxia and high temperature state(42±0.5)℃,and inbreathed a mixture gas made of 8.5% oxygen and 91.5% nitrogen ),after 30 min,the rabbits were taken out of,and the changes of microcirculation of mesentery were observed. The rabbits of myocardial ischemia groups were taken out of room temperature (25℃ with 30 min),and compared with the hypoxia and high temperature of myocardial ischemia group.Results In the myocardial ischemia group the microcirculation of mesentery in rabbits did not change significantly (P0.05).But in the hypoxia and high temperature of myocardial ischemia group mesenteric microvessel expanded(P0.05) and the speed of blood stream slowed down (P0.01).Conclusion After myocardial ischemia,hypoxia and high temperature can obviously change the microcirculation of mesentery in rabbits.