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[Influence of Ginkgo biloba L. exocarp polysaccharides on serum superoxide dismutase activity and malondialdehyde level in mice under different states].

An Xu, Hao Chen, Lin Wang, Qishen Wang

Abstract

OBJECTIVE: To study the influence of Ginkgo biloba exocarp polysaccharides(GBEP) on serum superoxide dismutase(SOD) activity and malondialdehyde(MDA) level in mice under different states. METHOD: GBEP was orally administrated to S180 bearing mice, cyclophosphamide(CTX) intoxicated mice and normal mice. The contents of SOD and MDA in the mice's blood were checked. RESULT: GBEP significantly enhanced SOD activity and decreased MDA content in S180 bearing mice. Similar effects were observed in CTX-intoxicated mice. In normal mice, however, no such effects were observed. CONCLUSION: GBEP may modulate the free radical system in mice under abnormal states.

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Key concepts: Malondialdehyde, Ginkgo biloba, Superoxide dismutase, Polysaccharide, Chemistry, Pharmacology, Dismutase, Biochemistry