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EXPERIMENTAL STUDY ON THE DISINFECTION CAPABILITY OF COMPOUND HYDROGEN PEROXIDE DISINFECTANT

Xiao Wang, Ping Yi, Wenming Zeng

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Abstract

[Objective] To study the disinfection of compound hydrogen peroxide disinfectant. [Methods] Suspension quantitative test and toxicity test were used to perform experimental observation on germicidal efficacy and stability of this compound disinfectant. [Results] The killing logarithm values of Candida albicans, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli in suspension exposed to the disinfection of compound hydrogen peroxide 31.31g / L with killing log value above 4.00 for 3min, 2min and 1min were ﹥4.00 and ﹥5.00. After the stock solution of the compound hydrogen peroxide disinfectant in airtight packing was stored at 54℃ for 14 days, its hydrogen peroxide content of the disinfectant decreased by 3.74%. The acute oral LD50 of its stock solution was ﹥5 000 mg / kg, the rabbit skin irritation score was zero. [Conclusion] The compound hydrogen peroxide disinfectant showed characteristics of non-toxic, non-irritant and non-micronucleus disinfectant with good and stable germicidal effect.

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What this paper is about

[Objective] To study the disinfection of compound hydrogen peroxide disinfectant. [Methods] Suspension quantitative test and toxicity test were used to perform experimental observation on germicidal efficacy and stability of this compound disinfectant. [Results] The killing logarithm values of Candida albicans, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli in suspension exposed to the disinfection of compound hydrogen peroxide 31.31g / L with killing log value above 4.00 for 3min, 2min and 1min were ﹥4.00 and ﹥5.00. After the stock solution of the compound hydrogen peroxide disinfectant in airtight packing was stored at 54℃ for 14 days, its hydrogen peroxide content of the disinfectant decreased by 3.74%. The acute oral LD50 of its stock solution was ﹥5 000 mg / kg, the rabbit skin irritation score was zero. [Conclusion] The compound hydrogen peroxide disinfectant showed characteristics of non-toxic, non-irritant and non-micronucleus disinfectant with good and stable germicidal effect.

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Available abstract

[Objective] To study the disinfection of compound hydrogen peroxide disinfectant. [Methods] Suspension quantitative test and toxicity test were used to perform experimental observation on germicidal efficacy and stability of this compound disinfectant. [Results] The killing logarithm values of Candida albicans, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli in suspension exposed to the disinfection of compound hydrogen peroxide 31.31g / L with killing log value above 4.00 for 3min, 2min and 1min were ﹥4.00 and ﹥5.00. After the stock solution of the compound hydrogen peroxide disinfectant in airtight packing was stored at 54℃ for 14 days, its hydrogen peroxide content of the disinfectant decreased by 3.74%. The acute oral LD50 of its stock solution was ﹥5 000 mg / kg, the rabbit skin irritation score was zero. [Conclusion] The compound hydrogen peroxide disinfectant showed characteristics of non-toxic, non-irritant and non-micronucleus disinfectant with good and stable germicidal effect.

Key concepts: Disinfectant, Hydrogen peroxide, Stock solution, Chemistry, Candida albicans, Staphylococcus aureus, Microbiology, Pseudomonas aeruginosa

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