Clinical study on the adjustment of vaginal dysbacteriosis after spontaneous labor with living preparation of lactobacillus.

Objective To study the change of the vaginal bacterial flora after spontaneous labor,and its harm to lying-in women,and discuss the effect of living preparation of lactobacillus on regulating vaginal dysbacteriosis after vaginal delivery.Methods Vaginal pH degree was explored respectively in 57 cases of normal healthy women,50 cases of late pregnancy women and 45 cases of vaginal labor women.At the same time,bacterial culture of vaginal secretion from these women were performed.Besides,72 cases of lying-in women who had adopted spontaneous labor and accepted general callback after 42 days after delivery were allocated into two groups randomly:living preparation of lactobacillus group(42 cases)and control group(30 cases).42 cases were treated by living preparation of Lactobacillus for 10 days continuously.Lying-in women in the control group who had suffered from vaginal infection were treated by compound metronidazole suppository or miconazole for 10 days continuously.The prevalence of vaginitis in two groups were compared and analyzed.Results Detectable rate of vaginal lactobacillus in lying-in women was lower significantly than that in pregnant women and normal healthy women(P0.01).Vaginal pH in lying-in women was higher than that in normal healthy women.There was significant difference between two groups(P0.01).Anaerobe proportion came down,while abnormal bacilli and conditioned pathogen increased in vagina of lying-in women.The incedence rate of bacterial vagiosis(BV)and vulvovaginal candidiasis(VVC)in women who had adopted spontaneous labor was 15.3% after 42 da0ys after delivery,while three months the incedence rate of BV and VVC of living preparation of lactobacillus group was both lower than that of control group(P0.05).Conclusions Normallabor can lead to vaginal dysbacteriosis and make lying-in women to be sensitive to BV and VVC.The application of living preparation of lactobacilus can restore the predominant status of lactobacillus in vagina,which play a vital role in preventing and curing BV and VVC after delivery.