The Clinical Study and Significance of Micro-ecological Mechanism in Vagina

Objective:To investigate vaginal micro-ecological status in community population.The objective was to provide a new way for prevent and cure lower reproductive tract infections.Methods:313 women of childbearing age(including 74 vaginitis cases) were selected randomly by cluster sub-sampling.The group case control method was used for data analysis.Results:The pH mean value was 4.4 in disorder group of vaginal micro-ecology,which was significant higher than 4.0 in normal group of vaginal micro-ecology(t=6.3581,P0.01).But it did not exceed the normal extent of the vaginal acidity.Moreover pH mean value among the vaginitis groups had more significant increase(all P0.01),which had exceeded the normal extent of the vaginal acidity,as compared to the normal group.The detection rates of lactobacillus and H2O2(+) in vagina among disorder group of vaginal micro-ecology were significantly lower than normal group(all P0.01).And the detection rates of these two indices among vaginitis group had more significant decrease compared with the normal group(all P0.01).The detection rate of vaginal lactobacillus in patients with vaginatis was also significantly lower than women without vaginitis(27.0% vs 74.9%,P0.01).The lower detection rate of vaginal lactobacillus,the higher risk of common vaginitis(all P0.01).Conclusions:The increasing of vaginal pH value could be considered as an early warning signal of abnormal vaginal micro-ecology.The detection rate of lactobacillus in vagina could be used as an index for monitoring vaginal health state and rehabilitation level after RTIs therapy.