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Radioimmunoscintigraphy of Ovarian Tumours with Tc-99m Labelled Monoclonal Antibody-170

C. Alexander, C Villena-Heinsen, L Trampert, S. Lung-Kurt, E. Oberhausen, W. Schmidt

Abstract

The present publication reflects our first experiences using the Tc-99m labelled monoclonal antibody MAb-170 for diagnostic use in patients with ovarian tumours. The collective included 10 patients suspected to have ovarian carcinoma. The results showed a sensitivity of 100 percent, the specificity was 100 % for adenocarcinoma and 71 % for ovarian carcinoma. In conclusion Tc-99m MAb-170 is a promising radiopharmaceutical for the detection of ovarian carcinoma.

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Key concepts: Ovarian carcinoma, Monoclonal antibody, Ovarian carcinomas, Medicine, Ovary, Ovarian cancer, Adenocarcinoma, Carcinoma