Effect of Banhasasimtang on carbon tetrachloride induced hepatoxicity in rats.

The purpose of this study is to observe the effect of Banhasasimtang on serum reaction in treated rats. In this study the experimental rats divided five group(Normal, Control, Sample A, Sample B and Sample C group) Under the same condition Normal group was fed basal diet and water, Control group was injected carbon tetrachloride( 0.5ml/kg) and basal diet for 2 weeks, Sample A group was injected carbon tetrachloride( 0.5ml/kg) and fed the Banhasasimtang extract(10ml/kg) for 2 weeks, Sample B group was fed the Banhasasimtang extract(10ml/kg) for 2 weeks and injected carbon tetrachloride( 0.5ml/kg), Sample C group was fed the Banhasasimtang extract(10ml/kg) for 2 weeks. The change of GOT, GPT, , ALP, LDH activity and Bilirubin level in blood serum. The obtained results are summarized as follows: 1. In the change of GOT GPT contents, as compared with control group, sample group was significantly decreased. 2. In the change of contents, as compared with control group, sample group was significantly decreased. 3. In the change of ALP contents, as compared with control group, sample group was significantly decreased. 4. In the change of LDP contents, as compared with control group, sample group was significantly decreased. 5. In the change of Bilirubin contents, as compared with control group, sample group was significantly decreased.