2011Oxford University Press eBooksRequires access

Introduction to Glycobiology

Maureen E. Taylor, Kurt Drickamer

Open publisher page 151 citations

Abstract

Introduction to Glycobiology considers the impact of sugars on biological systems, explaining their function at the molecular, cellular, and organismal level. It is made up of two parts. Part 1 looks at the structures and biosynthesis of glycans and includes chapters that examine concepts of glycobiology, N-linked glycosylation, O-linked glycosylation, and glycolipids and membrane protein glycosylation. There are also chapters on enzymology and the cell biology of glycosylation, analysis of glycan structures, and conformations of oligosaccharides. Part 2 focuses on glycans in biology. This section looks at the following topics: the effects of glycosylation on protein structure and function; carbohydrate recognition in cell adhesion and signalling; glycoprotein trafficking in cells and organisms; glycobiology of plants, bacteria, and viruses; glycobiology and development; glycosylation and disease; and the future of glycobiology.

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What this paper is about

Introduction to Glycobiology considers the impact of sugars on biological systems, explaining their function at the molecular, cellular, and organismal level. It is made up of two parts. Part 1 looks at the structures and biosynthesis of glycans and includes chapters that examine concepts of glycobiology, N-linked glycosylation, O-linked glycosylation, and glycolipids and membrane protein glycosylation. There are also chapters on enzymology and the cell biology of glycosylation, analysis of glycan structures, and conformations of oligosaccharides. Part 2 focuses on glycans in biology. This section looks at the following topics: the effects of glycosylation on protein structure and function; carbohydrate recognition in cell adhesion and signalling; glycoprotein trafficking in cells and organisms; glycobiology of plants, bacteria, and viruses; glycobiology and development; glycosylation and disease; and the future of glycobiology.

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Available abstract

Introduction to Glycobiology considers the impact of sugars on biological systems, explaining their function at the molecular, cellular, and organismal level. It is made up of two parts. Part 1 looks at the structures and biosynthesis of glycans and includes chapters that examine concepts of glycobiology, N-linked glycosylation, O-linked glycosylation, and glycolipids and membrane protein glycosylation. There are also chapters on enzymology and the cell biology of glycosylation, analysis of glycan structures, and conformations of oligosaccharides. Part 2 focuses on glycans in biology. This section looks at the following topics: the effects of glycosylation on protein structure and function; carbohydrate recognition in cell adhesion and signalling; glycoprotein trafficking in cells and organisms; glycobiology of plants, bacteria, and viruses; glycobiology and development; glycosylation and disease; and the future of glycobiology.

Key concepts: Glycobiology, Glycosylation, Glycan, Function (biology), Biology, Glycoprotein, Biochemistry, Computational biology

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