2023IUPHAR/BPS Guide to Pharmacology CITEOpen access

SLC25 family of mitochondrial transporters in GtoPdb v.2023.1

Edmund R.S. Kunji

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Abstract

Mitochondrial carriers are nuclear-encoded proteins, which translocate solutes across the inner mitochondrial membrane. Mitochondrial carriers are functional as monomers and have six TM alpha-helices and the termini in the mitochondrial intermembrane space.

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Mitochondrial carriers are nuclear-encoded proteins, which translocate solutes across the inner mitochondrial membrane. Mitochondrial carriers are functional as monomers and have six TM alpha-helices and the termini in the mitochondrial intermembrane space.

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Available abstract

Mitochondrial carriers are nuclear-encoded proteins, which translocate solutes across the inner mitochondrial membrane. Mitochondrial carriers are functional as monomers and have six TM alpha-helices and the termini in the mitochondrial intermembrane space.

Key concepts: Mitochondrial carrier, Mitochondrial intermembrane space, Intermembrane space, Translocase of the inner membrane, Inner mitochondrial membrane, Mitochondrion, ATP–ADP translocase, Mitochondrial membrane transport protein

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