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2023•Applied and Environmental MicrobiologyOpen access

PBP2b Mutations Improve the Growth of Phage-Resistant Lactococcus cremoris Lacking Polysaccharide Pellicle

H. Guérin, Pascal Quénée, Simon Palussière, Pascal Courtin, Gwenaëlle André, Christine Péchoux, Vlad Costache, Jennifer Mahony, Douwe van Sinderen, Saulius Kulakauskas, Marie‐Pierre Chapot‐Chartier

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Abstract

mutants resistant to bacteriophage infection with a restored fitness. This study provides an approach to isolate non-GMO phage-resistant L. cremoris and L. lactis strains, which can be applied to strains with technological functionalities. Also, our results highlight for the first time the link between peptidoglycan and cell wall polysaccharide biosynthesis.

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mutants resistant to bacteriophage infection with a restored fitness. This study provides an approach to isolate non-GMO phage-resistant L. cremoris and L. lactis strains, which can be applied to strains with technological functionalities. Also, our results highlight for the first time the link between peptidoglycan and cell wall polysaccharide biosynthesis.

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Available abstract

mutants resistant to bacteriophage infection with a restored fitness. This study provides an approach to isolate non-GMO phage-resistant L. cremoris and L. lactis strains, which can be applied to strains with technological functionalities. Also, our results highlight for the first time the link between peptidoglycan and cell wall polysaccharide biosynthesis.

Key concepts: Lactococcus lactis, Lactococcus, Mutant, Biology, Bacteriophage, Peptidoglycan, Microbiology, Bacteria

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PBP2b Mutations Improve the Growth of Phage-Resistant Lactococcus cremoris Lacking Polysaccharide Pellicle — Research Paper | ScholarLens