2022•Royal Society of Chemistry eBooksRequires access
Nitration Reactions
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Abstract
Nitration is the introduction of a nitro group into an organic molecule or compound. Nitration may take effect on carbon (C-nitration: most common, for example, nitration of benzene to afford mono-, di- (and tri) nitrobenzene as solvents or useful synthetic intermediates), oxygen (O-nitration: for example, nitration of glycerol to afford glyceryl trinitrate used to treat angina) and nitrogen (N-nitration). This chapter focuses on C-nitration of aromatic compounds only.