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Azithromycin effective in preventing MAC.

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Abstract

A study concluded that for the prevention of disseminated Mycobacterium avium complex in patients with advanced HIV infection once-weekly dosing of azithromycin is a simpler and more effective regimen than daily rifabutin. The California Collaborative Treatment Group researchers found that azithromycin alone or in combination with rifabutin is more effective than rifabutin alone. Azithromycin does not interact with other commonly-prescribed medicines for AIDS patients. Azithromycin achieves high levels at the site of infection.

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What this paper is about

A study concluded that for the prevention of disseminated Mycobacterium avium complex in patients with advanced HIV infection once-weekly dosing of azithromycin is a simpler and more effective regimen than daily rifabutin. The California Collaborative Treatment Group researchers found that azithromycin alone or in combination with rifabutin is more effective than rifabutin alone. Azithromycin does not interact with other commonly-prescribed medicines for AIDS patients. Azithromycin achieves high levels at the site of infection.

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Available abstract

A study concluded that for the prevention of disseminated Mycobacterium avium complex in patients with advanced HIV infection once-weekly dosing of azithromycin is a simpler and more effective regimen than daily rifabutin. The California Collaborative Treatment Group researchers found that azithromycin alone or in combination with rifabutin is more effective than rifabutin alone. Azithromycin does not interact with other commonly-prescribed medicines for AIDS patients. Azithromycin achieves high levels at the site of infection.

Key concepts: Azithromycin, Rifabutin, Regimen, Dosing, Medicine, Antibiotics, Internal medicine, Pharmacology

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