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Antivirals key to MAC prevention regimen.

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Abstract

Prophylaxis for Mycobacterium avium complex (MAC) should be considered standard treatment for all patients with advanced HIV disease. MAC is the most common bacterial infection that affects AIDS patients. There are three effective agents that significantly reduce the risk of MAC--rifabutin, clarithromycin, and azithromycin. MAC prophylaxis is cost-effective, improves the quality of a patient's life, and improves overall survival by 25 to 32 percent.

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Available abstract

Key concepts: Rifabutin, Mycobacterium avium complex, Azithromycin, Medicine, Clarithromycin, Regimen, Mycobacterium avium-intracellulare infection, Intensive care medicine