2018American Society for Clinical Laboratory ScienceOpen access

Variable Hemagglutination Reactions with Ulex europaeus Lectin and Group O Erythrocytes

Justin R. Rhees, Caden M. Hall

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Abstract

ABSTRACT Group O red blood cells (RBCs) express the highest amount of H antigen of any other blood group and are therefore expected to demonstrate strong reactivity when tested with Ulex europaeus anti-H lectin, unless the RBCs are from individuals possessing the Bombay or para-Bombay phenotypes. We report several examples of group O RBCs not belonging to the aforementioned groups that consistently produced weak reactions with quality-controlled Ulex europaeus lectin.

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ABSTRACT Group O red blood cells (RBCs) express the highest amount of H antigen of any other blood group and are therefore expected to demonstrate strong reactivity when tested with Ulex europaeus anti-H lectin, unless the RBCs are from individuals possessing the Bombay or para-Bombay phenotypes. We report several examples of group O RBCs not belonging to the aforementioned groups that consistently produced weak reactions with quality-controlled Ulex europaeus lectin.

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Available abstract

ABSTRACT Group O red blood cells (RBCs) express the highest amount of H antigen of any other blood group and are therefore expected to demonstrate strong reactivity when tested with Ulex europaeus anti-H lectin, unless the RBCs are from individuals possessing the Bombay or para-Bombay phenotypes. We report several examples of group O RBCs not belonging to the aforementioned groups that consistently produced weak reactions with quality-controlled Ulex europaeus lectin.

Key concepts: Ulex europaeus, Lectin, Hemagglutination, Biology, Chemistry, Molecular biology, Agglutinin, Immunology

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Variable Hemagglutination Reactions with Ulex europaeus Lectin and Group O Erythrocytes — Research Paper | ScholarLens