Variable Hemagglutination Reactions with Ulex europaeus Lectin and Group O Erythrocytes
Justin R. Rhees, Caden M. Hall
Abstract
Justin R. Rhees, Caden M. Hall
Abstract
Group O red blood cells (RBCs) express the highest amount of H antigen of any other blood group and, therefore, are expected to demonstrate strong reactivity when tested with Ulex europaeus anti-H lectin, unless the RBCs are from individuals possessing the Bombay or para-Bombay phenotypes. We report several examples of group O RBCs not belonging to the aforementioned groups that consistently produced weak reactions with quality-controlled Ulex europaeus lectin.
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Group O red blood cells (RBCs) express the highest amount of H antigen of any other blood group and, therefore, are expected to demonstrate strong reactivity when tested with Ulex europaeus anti-H lectin, unless the RBCs are from individuals possessing the Bombay or para-Bombay phenotypes. We report several examples of group O RBCs not belonging to the aforementioned groups that consistently produced weak reactions with quality-controlled Ulex europaeus lectin.
Key concepts: Ulex europaeus, Lectin, Hemagglutination, Biology, Chemistry, Agglutinin, Antigen, Molecular biology