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2017•European Journal of Medicinal ChemistryOpen access

Design, synthesis and biological evaluation of quinoline derivatives as HDAC class I inhibitors

Chen Chen, Xuben Hou, Guohua Wang, Wenyan Pan, Xinying Yang, Yingkai Zhang, Hao Fang

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Key concepts: Vorinostat, Chemistry, Histone deacetylase, Pharmacophore, HDAC8, Quinoline, In vitro, Biochemistry

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