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Gastrointestinal hormones

Morton I. Grossman

Open publisher page 14 citations

Abstract

The aggregate mass of endocrine cells in the gut exceeds that of all other endocrine organs combined. These endocrine cells are scattered among the mucosal epithelial cells of the stomach and small intestine. There are three established gastrointestinal hormones—gastrin, secretin and cholecystokinin (CCK)—and a long list of candidates. Gastrin is found mainly in the non-acid-secreting antral mucosa of the stomach and to a lesser extent in the upper small intestine, particularly the first part of the duodenum. Secretin and CCK are found in the mucosa of the upper two-thirds of the small intestine; CCK is identical with pancreozymin, once believed to be a separate hormone.

About this research paper

What this paper is about

The aggregate mass of endocrine cells in the gut exceeds that of all other endocrine organs combined. These endocrine cells are scattered among the mucosal epithelial cells of the stomach and small intestine. There are three established gastrointestinal hormones—gastrin, secretin and cholecystokinin (CCK)—and a long list of candidates. Gastrin is found mainly in the non-acid-secreting antral mucosa of the stomach and to a lesser extent in the upper small intestine, particularly the first part of the duodenum. Secretin and CCK are found in the mucosa of the upper two-thirds of the small intestine; CCK is identical with pancreozymin, once believed to be a separate hormone.

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OpenAlex reports 14 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The aggregate mass of endocrine cells in the gut exceeds that of all other endocrine organs combined. These endocrine cells are scattered among the mucosal epithelial cells of the stomach and small intestine. There are three established gastrointestinal hormones—gastrin, secretin and cholecystokinin (CCK)—and a long list of candidates. Gastrin is found mainly in the non-acid-secreting antral mucosa of the stomach and to a lesser extent in the upper small intestine, particularly the first part of the duodenum. Secretin and CCK are found in the mucosa of the upper two-thirds of the small intestine; CCK is identical with pancreozymin, once believed to be a separate hormone.

Key concepts: Secretin, Gastrin, Enteroendocrine cell, Cholecystokinin, Internal medicine, Duodenum, Endocrine system, Small intestine

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