Assessment of the efficacy of antihistamine drugs in complex treatment of chronic itchingdermatoses

The authors give a review of current concepts of mechanisms of skin itching development for different types of chronic dermatoses. The authors also present the results of a study aimed at assessing the efficacy of different 2nd generation antihistamine drugs used for complex treatment of 83 patients aged 14-73 suffering from different chronic itching dermatoses (atopic dermatitis, eczema, pruritus, chronic urticaria, progressing psoriasis, lichen acuminatus, contact allergic dermatitis). The authors conclude that Glencet (levocetirizine) used in a complex therapy of dermatoses accompanied with itching can efficiently arrest both subjective itching sensations and objective clinical symptoms of the diseases as well as reliably (р < 0.001) reduce the term of inpatient care by 4.8 ± 2.3 on average. Glencet (levocetirizine) is a drug of choice among the 2nd generation antihistamine drugs used for treatment of chronic skin diseases accompanied with itching.