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2021•Pharmacognosy JournalOpen access

Effect of Muntingia calabura L. Leaf Extract on Blood Glucose Levels and Body Weight of Alloxan-Induced Diabetic Mice

Tridiganita Intan Solikhah, Gahastanira Permata Solikhah

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Abstract

MATERIALS AND METHODS Prepamiceion of animalsMale mice (Mus musculus L.), aged ± 3 months, weighing between 25-35 grams were used in this study.The cage used was a plastic caged covered with wire mesh.Every other day, the cage's bottom was coated in 1 cm high husks.The scientific range for light, moisture, and room temperature were adjusted.Ethical code, institutional, and national regulation on live animals were strictly observed.The Health Research Ethical Clearance Commission, Faculty of Dental Medicine, Airlangga University granted ethical permission for the animals used in this investigation, with the number 507/HRECC.FODM/XI/2020.

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MATERIALS AND METHODS Prepamiceion of animalsMale mice (Mus musculus L.), aged ± 3 months, weighing between 25-35 grams were used in this study.The cage used was a plastic caged covered with wire mesh.Every other day, the cage's bottom was coated in 1 cm high husks.The scientific range for light, moisture, and room temperature were adjusted.Ethical code, institutional, and national regulation on live animals were strictly observed.The Health Research Ethical Clearance Commission, Faculty of Dental Medicine, Airlangga University granted ethical permission for the animals used in this investigation, with the number 507/HRECC.FODM/XI/2020.

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Available abstract

MATERIALS AND METHODS Prepamiceion of animalsMale mice (Mus musculus L.), aged ± 3 months, weighing between 25-35 grams were used in this study.The cage used was a plastic caged covered with wire mesh.Every other day, the cage's bottom was coated in 1 cm high husks.The scientific range for light, moisture, and room temperature were adjusted.Ethical code, institutional, and national regulation on live animals were strictly observed.The Health Research Ethical Clearance Commission, Faculty of Dental Medicine, Airlangga University granted ethical permission for the animals used in this investigation, with the number 507/HRECC.FODM/XI/2020.

Key concepts: Glibenclamide, Alloxan, Diabetes mellitus, Traditional medicine, Body weight, Positive control, Medicine, Internal medicine

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Effect of Muntingia calabura L. Leaf Extract on Blood Glucose Levels and Body Weight of Alloxan-Induced Diabetic Mice — Research Paper | ScholarLens