2010•Journal of Brain and Nervous DiseasesRequires access

Changes and clinical significance of serum t-PA and PAI-1 in patients with progressive cerebral infarction

Zhimin Tang

Abstract

目的探讨血浆中组织型纤溶酶原激活物(t-PA)及其抑制物(PAI-1)在进展性脑梗死发病中的作用.方法采用发色底物显色法测定100例急性脑梗死患者不同时期血浆t-PA及PAI-1 水平变化,并根据神经功能缺损(SSS)评分判断是否发展为进展性脑梗死.60例健康体检者作为对照组.结果 100例急性脑梗死患者中有38例(38.0%)于7d内发展为进展性脑梗死,与无进展脑梗死患者比较,其发病后第1d...

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Key concepts: Cerebral infarction, Clinical significance, Cardiology, Medicine, Internal medicine, Psychology, Ischemia