Evaluation of antipyretic and analgesic activity of methanolic extract of Riveaornata (roxb.) Leaves

Riveaornatais a climbing or straggling shrub, widely distributed throughout the south Indian region. The juice of this plant is used topically in haemorrhagic diseases and piles. Arial parts of this plant possess anti-inflammatory, anti-bacterial and anti-oxidant activities. Traditionally, it is utilized to treat fever and to relieve the pain. Hence the methanolic extract of Riveaornata leaves (200mg/kg, p.o.) was examined for antipyretic activity in rats by Brewer’s yeast induced hyperpyrexia method using paracetamol (150mg/kg, p.o.) as a reference standard and analgesic activity in mice by tail immersion and hot plate method using diclofenac (10mg/kg, p.o.) as a reference standard. The result showed that methanolic extract of Riveaornata (MERO) possess significant antipyretic and analgesic activity.