Development of Micro-Magnetic Beads Filter for Blood Cell Separation on a Paper Analysis Chip

Blood plasma contains lots of biomarkers such as proteins and nucleic acids. However, preparation of the plasma is commonly operated in large research facilities by centrifugation. This research aids to develop a blood cell separation method on a paper microchip alongside the development of Point-of-Care Testing. In this study, the method of building a deposition barrier of micro-magnetic beads for solid and liquid separation inside a paper chip by magnetic force is investigated. The microscale thickness of a paper chip allows to effectively create and utilize the magnetic force to control micro-magnetic beads in a microfluidic flow.