2007•Journal of the Magnetics Society of JapanOpen access

Development of Magnetic Separator for Biomaterials Labeled by Magnetic Beads

Wataru Maeda, S. Yamada, M. Iwahara

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Abstract

Magnetic separation is an important method of purifying of cells or DNA. A properly designed magnetic separator causes less physical and chemical damage to a target and has a high separation rate. This paper presents a new high-throughput continuous magnetic separator for biomaterials labeled by magnetic beads. The separator consists of three rectangular coils, two circular coils, and a separation chamber. These instruments were designed by a numerically analyzing of the magnetic field and the movement of magnetic beads. A separation rate over 90% was obtained with this system in a separation test using magnetic beads.

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Magnetic separation is an important method of purifying of cells or DNA. A properly designed magnetic separator causes less physical and chemical damage to a target and has a high separation rate. This paper presents a new high-throughput continuous magnetic separator for biomaterials labeled by magnetic beads. The separator consists of three rectangular coils, two circular coils, and a separation chamber. These instruments were designed by a numerically analyzing of the magnetic field and the movement of magnetic beads. A separation rate over 90% was obtained with this system in a separation test using magnetic beads.

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Available abstract

Magnetic separation is an important method of purifying of cells or DNA. A properly designed magnetic separator causes less physical and chemical damage to a target and has a high separation rate. This paper presents a new high-throughput continuous magnetic separator for biomaterials labeled by magnetic beads. The separator consists of three rectangular coils, two circular coils, and a separation chamber. These instruments were designed by a numerically analyzing of the magnetic field and the movement of magnetic beads. A separation rate over 90% was obtained with this system in a separation test using magnetic beads.

Key concepts: Magnetic separation, Separator (oil production), Magnetic bead, Materials science, Magnetic field, Magnetic nanoparticles, Magnet, Chromatography

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