1996•Phytotherapy ResearchRequires access

Isolation and effects on serum lipid levels of polysaccharide fractions from Fucus vesiculosus

M. Lamela, M. J. Vázquez‐Freire, J.M. Calleja

Abstract

The effects of three polysaccharide fractions isolated from a Fucus vesiculosus extract on serum lipid levels were evaluated in Triton-induced hyperlipaemic rats. The isolation was carried out by anion-exchange chromatography, and all fractions were mainly composed of fucose and sulphate. When administered to rats, the dose assayed (5 mg/kg) significantly lowered triglyceride and total cholesterol levels by 50-60% and 15-35% respectively.

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Key concepts: Fucus vesiculosus, Polysaccharide, Fucose, Triglyceride, Chemistry, Isolation (microbiology), Cholesterol, Pharmacognosy