2021Biology Bulletin ReviewsRequires access

Cellular ATP Synthase

Е. В. Узлова, С. М. Зиматкин

Open publisher page 3 citations

Abstract

This review presents a collection and analysis of the currently available data on the structure and organization, localization, working mechanisms, and functions of the enzyme that synthesizes adenosine triphosphate (ATP), ATP synthase. It is universal (present in all prokaryotic and eukaryotic cells) in nature and is unique in its characteristics. The proper assembly and functioning of ATP synthase are the required conditions for the normal process of oxidative phosphorylation, the result of which is energy storage in the form of ATP. A large number of diseases, including neurodegenerative and mitochondrial diseases, are associated with ATP synthase disorders.

About this research paper

What this paper is about

This review presents a collection and analysis of the currently available data on the structure and organization, localization, working mechanisms, and functions of the enzyme that synthesizes adenosine triphosphate (ATP), ATP synthase. It is universal (present in all prokaryotic and eukaryotic cells) in nature and is unique in its characteristics. The proper assembly and functioning of ATP synthase are the required conditions for the normal process of oxidative phosphorylation, the result of which is energy storage in the form of ATP. A large number of diseases, including neurodegenerative and mitochondrial diseases, are associated with ATP synthase disorders.

Why it matters

OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

This review presents a collection and analysis of the currently available data on the structure and organization, localization, working mechanisms, and functions of the enzyme that synthesizes adenosine triphosphate (ATP), ATP synthase. It is universal (present in all prokaryotic and eukaryotic cells) in nature and is unique in its characteristics. The proper assembly and functioning of ATP synthase are the required conditions for the normal process of oxidative phosphorylation, the result of which is energy storage in the form of ATP. A large number of diseases, including neurodegenerative and mitochondrial diseases, are associated with ATP synthase disorders.

Key concepts: ATP synthase, Adenosine triphosphate, Biology, Oxidative phosphorylation, ATP synthase gamma subunit, Biochemistry, Enzyme, Mitochondrion

Related papers

Back to paper searchBrowse research topicsOriginal source
Cellular ATP Synthase — Research Paper | ScholarLens