ATP Synthase Stalk Subunits b , δ and ε: Structures and Functions in Energy Coupling

This chapter contains sections titled: Introduction ε Subunit of ATP Synthase Conformations of the ε Subunit in Crystal Structures of ATP Synthase and the γ′ε Subcomplex ε in the “Down” Conformation ε in the “Up” Conformation Biochemical Analyses of Conformations and Orientations of ε in ATP Synthase Role of the ε Subunit in ATP Synthase Rotation of ε During Hydrolysis Role of ε in the Formation of F1Fo and Inhibition of Soluble F1-ATPase ε as an Inhibitor in ATP Synthase Bidirectional Ratchet Model for ε Function in ATP Synthase Peripheral Stalk of ATP Synthase b Subunit Sequences Structure of E. coli b Membrane-spanning Domain Tether Domain Dimerization Domain δ-Binding Domain Proposed Structural Model of b Structure of δ Interaction of b and δ Position of the Peripheral Stalk in ATP Synthase Function of the Peripheral Stalk Conclusion References