Comparative study on diagnosis of refractory epilepsy by PET/CT,EEG and MRI

Objective To study the diagnostic value of PET/CT,EEG and MRI for foci localization with refractory epilepsy.Methods Fifty patients from December 2005 to December 2009 in our hospital with refractory epilepsy patients(male 32 cases,female 18 cases,age from 4 to 46,duration of disease from 5 to 25 years.All patients understood PET/CT,EEG and MRI and rate of epileptic diagnostic localization and consistency in PET/CT,EEG and MRI were analyzed and compared.Results PET/CT positive rate was 92%,with low metabolic foci in 38 cases,high metabolic foci in 5 cases,and both in 2 case.EEG positive rate was 74%(37 cases),MRI positive rate was 36%(18 cases) .Consistency of foci diagnostic localization between PET/CT and EEG was 72% .Consistency of foci diagnostic localization between PET/CT and MRI was 36% .Consistency of foci diagnostic localization between MRI and EEG was 32% .Conclusions PET/CT imaging is more sensitive than EEG and MRI in detecting epileptic foci of children in refractory cases.Consistency between PET/CT and EEG is well over that between MRI and EEG in foci localization.