Effect of baicalin and berberine on transport of nimodipine on primarycultured, rat brain microvascular endothelial cells
Dongmei, Zhang Zhang, Haiyan Haiyan, Liu -, LinXIE, Xiaodong
Abstract
Dongmei, Zhang Zhang, Haiyan Haiyan, Liu -, LinXIE, Xiaodong
Abstract
目的:调查 baicalin 和 berberine 是否越过血大脑障碍( BBB )影响运输 ofnimodipine ( NMD ) .Methods :主要有教养,老鼠大脑 microvascularendothelial 房间( rBMEC )是被使用一在里面 BBB.When 房间的 vitro 模型变得汇合,由 rBMEC 与或没有 baicalin 和 berberine 的 NMD 的thesteady状态举起是 measured.The effectsof baicalin ,从 rBMEC 的 NMD 的流出上的 berberine 也是 studied.Results : Baicalin ( 2-5 mug/mL )增加了 NMD ,和 baical 的举起
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目的:调查 baicalin 和 berberine 是否越过血大脑障碍( BBB )影响运输 ofnimodipine ( NMD ) .Methods :主要有教养,老鼠大脑 microvascularendothelial 房间( rBMEC )是被使用一在里面 BBB.When 房间的 vitro 模型变得汇合,由 rBMEC 与或没有 baicalin 和 berberine 的 NMD 的thesteady状态举起是 measured.The effectsof baicalin ,从 rBMEC 的 NMD 的流出上的 berberine 也是 studied.Results : Baicalin ( 2-5 mug/mL )增加了 NMD ,和 baical 的举起
Key concepts: Berberine, Baicalin, Chemistry, Nimodipine, Pharmacology, Biochemistry, Medicine, Chromatography