Survey of Antibiotic Resistance of E. coli from Different Sources in Tacheng Region in Xingjiang

In order to master the status of drug-resistance of E. coli from different sources and provide information for future establishing database of bacterial resistance in Tacheng Region,this study collected samples from farm and raising-households,including samples of drinking water( 12),feed( 49),bovine feces( 56) and ovine feces( 20),and isolated E. coli from samples. The resistance of isolated E. coli to clinical antimicrobial drugs was detected by agar dilution method,and the differences in resistance to E. coli from different sources were compared by chi square test. The results showed that resistance rate of E. coli from drinking water to enrofloxacin,ciprofloxacin,amoxicillin /clavulanic acid and ampicillin all reached 100%. Resistance rate of E. coli from feed to amoxicillin/clavulanic acid and ampicillin were 61. 2% and 51. 0%,respectively. Resistance rate of E. coli from bovine feces to amoxicillin /clavulanic acid and ciprofloxacin was 14. 3%. Resistance rate of E. coli from ovine feces to amoxicillin/clavulanic acid and ciprofloxacin were 40. 0% and 35. 0%,respectively. Resistance rate of E. coli from drinking water was significantly higher than that from bovine feces,ovine feces and feed to enrofloxacin,ciprofloxacin,amoxicillin /clavulanic acid and ampicillin( P0. 05). 0 resistant and 4 resistant E. coli strains from feed accounted for 38. 8%,0 resistant E. coli strains from bovine feces and ovine feces accounted for 78. 6% and 50. 5%,respectively. 4resistant E. coli strains from drinking water accounted for 100%. The above results indicated there were significant differences in resistance of E. coli from different sources to detected antibiotics,and the commonality was higher intermediate rate between E. coli from different sources to detected antimicrobial drugs,which suggested that there were risks of rapidly growing number of resistant E. coli,if not changing the medication regimen.