Investigation on Antimicrobial Drug Resistance to Escherichia coli Isolates from A Farm in Tacheng Xinjiang

In order to investigate commonly used antimicrobial drug resistance to Escherichia coli isolates from a farm in Tacheng,Xinjiang,the minimal inhibitory concentrations(MIC)of the antimicrobial drugs to these isolates from drinking water,feed,bovine feces and ovine feces were determined by the broth micro-dilution method.The results showed that:35 E.coli isolates were confirmed from 35 drinking water samples(100.0%),the resistance rates to amoxicillin/clavulanic acid and ampicillin were 31.4% and20%,respectively.13 E.coli isolates were confirmed from 15 feed samples(86.7%),the resistance rates to ampicillin,amoxicillin/clavulanic acid,apramycin,norfloxacin,enrofloxacin and gentamicin were30.8%,23.1%,15.4%,7.7%,7.7%and 7.7%,respectively.20 E.coli isolates were confirmed from20 bovine fecals samples(100.0%),the resistance rates to ampicillin,amoxicillin/clavulanic acid,enrofloxacin,gentamicin,ceftiofur,amikacin,norfloxacin and ciprofloxacin were 60.0%,50.0%,40.0%,40.0%,35.0%,25.0%,10.0%and 10.0%,respectively.55 E.coli isolates were confirmed from 55 ovine fecals samples(100.0%),the resistance rates to amoxicillin/clavulanic acid,ampicillin,gentamicin,ceftiofur,norfloxacin,enrofloxacin and amikacin were 25.5%,12.7%,5.5%,3.6%,1.8%,1.8%and1.8%,respectively.The multi-drug resistance of E.coli is serious in Tacheng Xinjiang.The clinical medication needs to be careful,and there may be a risk of fecal bacterial pollution to water and feed.