Preliminary clinical experience of one-stage endovascular embolization for multiple intracranial aneurysms

Objective To preliminarily investigate and summarize the technique and efficacy of one-stage endovascular embolization for treatment of multiple intracranial aneurysms.Methods Eighteen patients with multiple intracranial aneurysms,in whom 44 aneurysms were found,were treated by endovascular embolization in one-stage from Sep.2005 to Jun.2009.Thirty-two aneurysms were embolized with hydro-detachable coils,and twelve wide-necked aneurysms were embolized with intracranial stents(LEO stent or Enterprise stent) combined with hydro-detachable coils.The clinical and radiological follow-up period was 3-12 months after surgery.Results Embolization was successful in all patients,and the stent placement was optimal in 12.The total occlusion of aneurysmal cavities was achieved in 38 aneurysm,more than 95% of the aneurysmal cavities were occluded in 5 aneurysms and less than 95% in 1 aneurysm.No operative complication was found and all the patients recovered well.No rebleeding or cerebral thrombosis occurred during the period of 3-12 months clinical follow-up,and no aneurysmal recurrence or in-stent stenosis was found in 9 patients followed-up by digital substraction angiography(DSA).Conclusion Endovascular embolization in one-stage is a safe and effective technique for the treatment of multiple intracranial aneurysms,and the long-term efficacy still needs further observation.