2010•Zhongguo redai yixueRequires access

Survey of resistance of 713 Mycobacterium tuberculosis strains to antibiotics

Lin Shi-pin

Abstract

Aim To survey the resistance of Mycobacterium tuberculosis. Methods Drug sensitivity test was carried out by improved L-J culture drug susceptibility tes(tTB). Results Among the 1 754 Mycobacterium tuberculosis strains,713 strains were resistance to antibiotics with resistant rate of 41.0%;111 strains were multi-resistan with a rate of 6.3%; The resistance to SM,RFP,INH and EMB were 26.1%,25.3%,14.1% and 10.3% respectively. The resistant rate and MDR in young group was higher than that of the middle-aged group and was even higher than that of the senile group. Conclusion The drug resistance of Mycobacterium tuberculosis to antibiotics in Shenzhen show a ncreasing trend and effective measures be adopted.

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Key concepts: Mycobacterium tuberculosis, Antibiotics, Microbiology, Tuberculosis, Drug resistance, Mycobacterium, Biology, Medicine