2001中华医学杂志:英文版Requires access

Cytogenetic analysis in 61 couples with spontaneous abortions

Jiang Jing

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Abstract

Objective To examine the relationship between spontaneous abortion and chromosomal abnormalities Methods Couples who had one or more consecutive spontaneous abortions and had normal genitals were enrolled for cytogenetic karyotype analysis Results In the 61 couples, the detected incidence was 11 5%, with five Robertsonian translocations, one reciprocal translocation, and one pericentric inversion of chromosome 7 Conclusion Chromosomal abnormalities may play an important role in fetal wastage

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Objective To examine the relationship between spontaneous abortion and chromosomal abnormalities Methods Couples who had one or more consecutive spontaneous abortions and had normal genitals were enrolled for cytogenetic karyotype analysis Results In the 61 couples, the detected incidence was 11 5%, with five Robertsonian translocations, one reciprocal translocation, and one pericentric inversion of chromosome 7 Conclusion Chromosomal abnormalities may play an important role in fetal wastage

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Available abstract

Objective To examine the relationship between spontaneous abortion and chromosomal abnormalities Methods Couples who had one or more consecutive spontaneous abortions and had normal genitals were enrolled for cytogenetic karyotype analysis Results In the 61 couples, the detected incidence was 11 5%, with five Robertsonian translocations, one reciprocal translocation, and one pericentric inversion of chromosome 7 Conclusion Chromosomal abnormalities may play an important role in fetal wastage

Key concepts: Chromosomal translocation, Robertsonian translocation, Karyotype, Chromosomal inversion, Abortion, Chromosome analysis, Genetics, Biology

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