2009•Guoji yiyao weisheng daobaoRequires access
Study on the changes of plasma levels of ntbnp and crp in patients with acute cerebral infarction
LV Yan-l
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Abstract
Objective To explore the changes of plasma levels of NTBNP and CRP in patients with acute cerebral infarction and its possible pathophysiologic implications.Methods The level of plasma NTBNP and CRP of 40 patients with acute cerebral infarction,40 patients with subacute cerebral infarction and 30 healthy controls were determined by ELISA.Results The levels of NTBNP and CRP of patients with acute cerebral infarction were significantly higher than those in control and subacute cerebral infarction groups(P0.01),and the plasma of NTBNP and CRP in patients with 1arge area of infarction were significantly higher than those in patients with small area of infarction(P0.01).Conclusions Plasma NTBNP and CRP are increased significantly in patients with cerebral infarction,they possibly play the most important key role in the pathogenesis of cerebral infarction.