Chemical Constituents of Petroleum Ether Fraction of Lonicera macranthoides Roots

Objective: To study chemical constituents of petroleum ether fraction of the roots of Lonicera macranthoides. Methods:The chemical constituents were isolated and purified by several separation and purification techniques and their structures were elucidated by physicochemical properties and spectroscopic methods. Results: Six compounds were isolated from petroleum ether fraction of the roots of Lonicera macranthoides as 3α,16β-dihydroxyaphidicolane( 1),( 22 E,24R)-ergosta-6,9,22-trien-3β,5α,8α-triol( 2),( 22E)-5α,8α-epidioxyergosta-6,22-dien-3β-ol( 3),( 24S)-stigmast-4-en-3-one( 4),β-amyrin( 5) and β-amyrin acetate( 6). Conclusion:Compounds 1 ~ 3 and 6 are isolated from this genus for the first time. All the compounds are isolated from this plant for the first time. Compound 1 is a new natural product.