2020•Journal of Evidence Based Medicine and HealthcareOpen access

Study on Thyroid Dysfunction in Patients with Major Depressive Disorder

Tonjam Hemchand Singh, Haobijam Nirendrakumar Singh, Nongthonbam Surajkumar Singh

Abstract

BACKGROUND We wanted to evaluate serum levels of thyroid hormones (FT3, FT4 and TSH) among the patients with major depressive disorder (MDD) and determine the prevalence of hypothyroidism among MDD patients. METHODS This cross-sectional study was conducted in the Department of Psychiatry, JNIMS for a period of one year from Nov. 2017 to Oct. 2018. After obtaining informed consent, confirmed cases of MDD who attended JNIMS psychiatry OPD were selected for study. RESULTS Prevalence of hypothyroidism among MDD patients was found to be 24 % and more in females, patients from low-socio-economic status and in older age group. CONCLUSIONS Considering the higher prevalence of hypothyroidism in females and low socioeconomic status among the major depressive disorder patients, attention has to be paid to screening thyroid hormone testing in all major depressive disorders and early treatment of hypothyroidism. KEYWORDS Euthyroid, Hypothyroidism, Major Depressive Disorder

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Key concepts: Medicine, Major depressive disorder, Euthyroid, Thyroid disorder, Socioeconomic status, Thyroid dysfunction, Thyroid, Depressive symptoms