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2021•International Journal of Advanced Research in MedicineOpen access

Assessment of thyroid dysfunction in beta thalassemia patients

Nagendra Singh Chauhan

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Abstract

Background: Thalassemia is the most common inherited monogenic disorder in the world. The present study was conducted to assess thyroid dysfunction in thalassemia patients.Materials & Methods: 84 children with beta thalassemia major of both genders were assessed for serum total thyroxine (T4), thyroid-stimulating hormone (TSH) and Serum ferritin levels were obtained. TSH and T4 concentration were analyzed by ELISA.Results: There were 64 euthyroid and 20 hypothyroid patients. 40 male and 24 females euthyroid patients and 12 males and 8 hypothyroid patients. The difference was significant (P

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Background: Thalassemia is the most common inherited monogenic disorder in the world. The present study was conducted to assess thyroid dysfunction in thalassemia patients.Materials & Methods: 84 children with beta thalassemia major of both genders were assessed for serum total thyroxine (T4), thyroid-stimulating hormone (TSH) and Serum ferritin levels were obtained. TSH and T4 concentration were analyzed by ELISA.Results: There were 64 euthyroid and 20 hypothyroid patients. 40 male and 24 females euthyroid patients and 12 males and 8 hypothyroid patients. The difference was significant (P

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Available abstract

Background: Thalassemia is the most common inherited monogenic disorder in the world. The present study was conducted to assess thyroid dysfunction in thalassemia patients.Materials & Methods: 84 children with beta thalassemia major of both genders were assessed for serum total thyroxine (T4), thyroid-stimulating hormone (TSH) and Serum ferritin levels were obtained. TSH and T4 concentration were analyzed by ELISA.Results: There were 64 euthyroid and 20 hypothyroid patients. 40 male and 24 females euthyroid patients and 12 males and 8 hypothyroid patients. The difference was significant (P

Key concepts: Euthyroid, Medicine, Thyroid dysfunction, Internal medicine, Thalassemia, Thyroid, Endocrinology, Ferritin

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