2020PubMedOpen access

Acquired rare recurrent EGFR mutations as mechanisms of resistance to Osimertinib in lung cancer and in silico structural modelling.

Lin Lin, Qiang Lu, Ran Cao, Qiuxiang Ou, Yutong Ma, Hua Bao, Xue Shen Wu, Yang Shao, Zhaoxia Wang, Bo Shen

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Abstract

-mutated lung cancer. We identified a collection of coexistent EGFR rare mutations and provided possible guidance for those patients who progressed on the first-line treatment of Osimertinib.

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What this paper is about

-mutated lung cancer. We identified a collection of coexistent EGFR rare mutations and provided possible guidance for those patients who progressed on the first-line treatment of Osimertinib.

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OpenAlex reports 20 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

-mutated lung cancer. We identified a collection of coexistent EGFR rare mutations and provided possible guidance for those patients who progressed on the first-line treatment of Osimertinib.

Key concepts: Osimertinib, Lung cancer, Gefitinib, Medicine, Cancer research, In silico, Oncology, Mutation

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Acquired rare recurrent EGFR mutations as mechanisms of resistance to Osimertinib in lung cancer and in silico structural modelling. — Research Paper | ScholarLens