2020•International Journal of Materials and ChemistryOpen access
Synthesis and Biological Activity of Succinates 3,15,16,18 Tetrahydroxy 9-13-Epoxylabdane
Sobirova Fotima, Esanov Rakhmat, Elmurodov Laziz, Nataliya Vypova, Alimjon Matchanov
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Abstract
The data on the synthesis of lagochiline succinates with succinic anhydride is presented in the article. The structure of the resulting compound was found out by physicochemical methods of analysis, mass spectrometry data and a calculation method. The purpose of this work was to synthesize a number of succinates of the diterpenoid lagochilin and obtain water-soluble salts, as well as to study the physicochemical and spectral properties and structure of the synthesized compounds by mass spectrometry, 1H NMR and a calculation method. To establish the chemical structure of the synthesized compounds, the method of ultra high performance liquid chromatography-mass spectrometry was applied (HPLS-MС/MС).To establish the chemical structure of the synthesized compounds, the method of ultra high performance liquid chromatography-mass spectrometry was applied (HPLS-MС/MС).